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Andrew Simpson - Having identified these previously unknown mutations in key cancer causing genes, we will hopefully enable the development of small molecules and antibodies to regulate their abnormal function and thus inhibit the growth of cancerous cells. This collaborative study exemplifies exactly what our coalition was formed to do -- leverage our individual institution's expertise to collectively discover new druggable targets through genome sequencing and functional genomic analysis.

Having identified these previously unknown mutations in key cancer causing genes, we will hopefully enable the development of small molecules and antibodies to regulate their abnormal function and thus inhibit the growth of cancerous cells. This collaborative study exemplifies exactly what our coalition was formed to do -- leverage our individual institution's expertise to collectively discover new druggable targets through genome sequencing and functional genomic analysis.

Andrew Simpson
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